Advanced software tools for toxicology, drug discovery, and endocrine disruption studies on zebrafish larvae for human and environmental health.
DanioTracker is a deep learning-based software for analyzing videos of zebrafish larvae. It automates in-depth behavioral analysis of escape swims, helping to uncover toxicant-specific neuromuscular disruptions, assess balance loss, and quantify epileptic-like seizures.
The Zebrafish Obesogenic Test (ZOT) Analysis Software is a deep-learning program for processing ZOT fluorescence images. It enhances protocol reproducibility and image processing speed, providing valuable information for environmental and human risk assessments.
DanioAChE is a desktop image-analysis platform for AI-based quantification of acetylcholinesterase staining in zebrafish larvae, designed for cholinergic toxicology studies of organophosphorus nerve agents and pesticides, and for screening brain-penetrant antidotes that restore central AChE function.
Zebrafish Research is the software portal of BioDevs, a scientific software company based in Talence, near Bordeaux (Nouvelle-Aquitaine, France). It publishes DanioTracker, ZOTAS and DanioAChE, AI-based tools for zebrafish larvae research in toxicology, drug discovery and endocrine disruption.
The tools are developed by Théo Mercé (also written Theo Merce), PhD, founder of BioDevs, with Emilien Reaud, MSc. They come from peer-reviewed research on zebrafish larval behavior, obesogen screening and organophosphorus toxicity.
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